Pipeline — registered trials by phase
A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy
— · Severe Eosinophilic Asthma · Recruiting · est. 2028-12-31
European Study of Cardiovascular Risk
— · Cardiovascular Risk Factors, Hyperlipidemia, Hypertension · Completed
Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia
— · Schizophrenia · Completed · est. 2011-08
An Open-Label Study of Once-Daily Oral Administration of Esomeprazole 40 mg in Patients With Symptoms of Gastroesophageal Reflux Disease (GERD)
— · GERD · Completed
Subjective Well Being of Patients Receiving Atypical Antipsychotics as Monotherapy or Cotherapy With Mood Stabilizers
— · Bipolar Disorder · Completed · est. 2008-07
An Open Label Non-Interventional Evaluation of the Effect of Adjuvant Hormonal Treatment of Postmenopausal Women Wih Early Breast Cancer With Aromatase Inhibitors on Bone Mineral Density and Bone Fracture Rate in Daily Practice
— · Breast Cancer, Osteoporosis · Completed
Metabolic Syndrome Observation on a Regional Basis
— · Metabolic Syndrome · Completed · est. 2010-10
Benralizumab Patient Access Programme Study: Retrospective Study in UK Severe Asthma Centres
— · Asthma · Completed · est. 2022-02-28
Symptoms and Management Strategies in Gastroesophageal Reflux Disease (GERD)
— · Gastroesophageal Reflux Disease · Completed
Prospective Multicentre Phase-IV Clinical Trial of Olaparib in Indian Patients With Ovarian and Metastatic Breast Cancer
— · Ovarian Cancer, Breast Cancer · Completed · est. 2022-09-30
To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer
— · BRCA or HRR+ Mutated Ovarian Cancer Patients · Completed · est. 2020-04-17
Observational Study to Evaluate Efficacy and Remission Status for Schizophrenia Patients Under Atypical Treatment
— · Schizophrenia · Completed · est. 2010-09
Observational Study to Evaluate Bipolar Disorder Symptoms in Patients Presented With Schizophrenia or Depression
— · Schizophrenia, Schizoaffective Disorder, Recurrent Depression · Completed · est. 2010-11
PRostate Olaparib Real World Evidence Study
— · Metastatic Castration-resistant Prostate Cancer · Active Not Recruiting · est. 2028-10-13
A Real World Study to Capture Clinical and Patient Centered Outcomes in Adults With Severe Eosinophilic Asthma Treated With Benralizumab.
— · Severe Eosinophilic Asthma · Completed · est. 2025-04-13
A NIS Registry of the Prospective Structured Care In Acute Coronary Syndrome
— · Acute Coronary Syndrome · Completed · est. 2014-08
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
— · Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis · Completed · est. 2011-08
BENEFITS OF ACLIDINIUM BROMIDE IN THE RELIEF OF COPD SYMPTOMS INCLUDING COUGH
— · Pulmonary Disease, Chronic Obstructive · Completed · est. 2015-11
Study of Incidence of Drug-induced Upper Gastrointestinal Bleeding
— · Upper Gastrointestinal Bleeding · Completed · est. 2011-06
A Non-Interventional Study To Evaluate Diabetes Related Quality Of Life, Frequency And Impact Of Hypoglycemia In T2DM
— · Type II Diabetes Mellitus · Completed · est. 2013-02
Non-inteRvEntional Study to Observe rAtionaLe to Select add-on TherapY for Type 2 Diabetes Inadequately Controlled With Metformin.
— · Type 2 Diabetes Mellitus · Completed · est. 2016-07-28
Real World Evidence of Long-term Safety and Efficacy in Patients Treated With Durvalumab After Concurrent Chemoradiation for Unresectable Stage III NSCLC
— · Carcinoma, Non-Small-Cell Lung · Completed · est. 2024-01-11
Description of Drug Utilization and Assessment of Impact of Saxagliptin on Health Status of Patients With Type 2 Diabetes in France
— · Type 2 Diabetes Mellitus (T2D) · Completed · est. 2015-06
HER2(Human Epidermal Growth Factor Receptor 2) -Positive Metastatic Breast Cancer in Russia
— · Breast Cancer · Completed · est. 2024-03-29
PROMET-BR - Molecular Profiling of Metastatic Prostate Cancer: a Brazilian Cohort
— · Metastatic Prostate Cancer · Not Yet Recruiting · est. 2027-03-31
Study to Collect Samples for MIST Analysis of Zibotentan and Bioavailability of Zibotentan and Dapagliflozin in Heatlhy Participants
— · Chronic Kidney Disease · Completed · est. 2021-10-22
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 in Japanese Healthy Participants With Single and Multiple Ascending Dose Administration
— · Heart Failure · Completed · est. 2019-05-02
A Study of MEDI-575 in Patients With Advanced Solid Malignancies
— · Advanced Solid Malignancies · Completed · est. 2012-11
Safety, Tolerability and PK of AZD1152 in Patients With Relapsed Acute Myeloid Leukaemia (AML)
— · Acute Myeloid Leukaemia · Completed · est. 2009-08
A PET Study to Determine Biodistribution and Binding Characteristics of [11C]AZ14132516 in Healthy Participants
— · Healthy Volunteers · Completed · est. 2023-07-11
A Study to Assess the Pharmacokinetics of AZD6793 When Administered Alone and in Combination With Itraconazole in Healthy Participants.
— · Healthy Participants · Completed · est. 2024-10-05
AZD6738 First Time in Patient Multiple Ascending Dose Study
— · 11q-deleted Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL),, Prolymphocytic Leukaemia (PLL), B Cell Lymphomas · Completed · est. 2013-12
Drug Interaction Study to Asses Multiple Doses of ZD4054 (Zibotentan)
— · Healthy · Completed · est. 2008-08
Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin
— · Healthy Volunteers, Pharmacokinetics · Completed · est. 2008-08
Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors
— · Advanced Solid Tumors, Pancreatic Cancer, Non Small Cell Lung Cancer · Completed · est. 2019-09-23
Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors
— · Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor · Completed · est. 2016-03
Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)
— · Advanced Non Small Cell Lung Cancer, Advanced (Inoperable) Non Small Cell Lung Cancer · Completed · est. 2015-04-03
To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects
— · Solid Tumors · Completed · est. 2014-11
Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell Carcinoma
— · Carcinoma, Renal Cell · Completed · est. 2010-05
Drug-Drug Interaction Study With AZD9291 and Omeprazole in Healthy Volunteers
— · Healthy Volunteer · Completed · est. 2015-01
A Study to Evaluate Safety, Tolerability and P-Glucose After Multiple Ascending Oral Doses of AZD1656 in Type 2 Diabetes
— · Type 2 Diabetes · Completed · est. 2009-04
A Phase I, Open-Label, Multicentre Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MEDI4736 in Patients With Advanced Solid Tumours
— · Advanced Solid Tumors · Completed · est. 2018-03-01
A Study to Investigate the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel When Given Alone and in Combination With Baxdrostat in Healthy Females of Non-childbearing Potential
— · Healthy Participants · Completed · est. 2025-02-03
A Study Designed to Assess the Mass Balance Recovery, Absorption, Metabolism, Excretion of [14C]AZD4954 and the Absolute Bioavailability of AZD4954
— · Healthy Participants · Not Yet Recruiting · est. 2026-12-17
The PK and PD of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM
— · Type 1 Diabetes Mellitus · Completed · est. 2016-06
Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes
— · Type 2 Diabetes · Completed · est. 2012-11
Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK
— · Healthy Volunteers Pharmacokinetic Study · Completed · est. 2014-05
Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
— · Recurrent or Metastatic PD-L1-positive Squamous Cell Carcinoma of the Head and Neck · Completed · est. 2016-09-26
A Phase-II Study Of TOMUDEX Plus Radiotherapy In Subject With Inoperable or Recurrent Rectal Cancer
— · Inoperable or Recurrent Rectal Cancer · Completed
14473 - D9126C00001 Proof of Principle Study - Effect of AZD2066 on Transient Lower Esophageal Sphincter Relaxations
— · Reflux Episodes · Completed
Ph II Study to Evaluate Olaparib With Abiraterone in Treating Metastatic Castration Resistant Prostate Cancer.
— · Metastatic Castration-resistant Prostate Cancer · Completed · est. 2017-09-22
Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma
— · Asthma · Completed · est. 2026-01-07
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
— · Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast · Active Not Recruiting · est. 2023-01-25
A Study to Evaluate the Safety and Efficacy of Cotadutide Given by Subcutaneous Injection in Adult Participants With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis
— · Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis · Completed · est. 2024-04-19
A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK
— · Liver Cirrhosis · Completed · est. 2024-12-11
Budesonide / Formoterol in Treatment of Exacerbations of COPD
— · Chronic Obstructive Pulmonary Disease · Completed
Dapagliflozin Evaluation in Patients With Inadequately Controlled Type 1 Diabetes
— · Type 1 Diabetes Mellitus · Completed · est. 2017-01-04
Savolitinib vs. Sunitinib in MET-driven PRCC.
— · Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms · Active Not Recruiting · est. 2019-08-18
Phase III Double-blind, Placebo-controlled Study of AZD7442 for Post- Exposure Prophylaxis of COVID-19 in Adults
— · COVID-19 · Completed · est. 2021-04-07
STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma
— · Severe Eosinophilic Asthma · Completed · est. 2026-05-13
Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects
— · Hyperkalemia · Completed · est. 2022-01-03
Two Different Regimens of Nolvadex in Preventing Gynecomastia Induced by Casodex 150 mg in Patients With Prostate Cancer
— · Prostate Cancer · Completed · est. 2007-10
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
— · Obesity or Overweight · Recruiting · est. 2028-08-11
A Study to Evaluate the Safety of MEDI8897 for the Prevention of Medically Attended Respiratory Syncytial Virus(RSV) Lower Respiratory Track Infection (LRTI) in High-risk Children
— · Respiratory Syncytial Virus Infections · Completed · est. 2021-05-03
New Version Pulmicort Turbuhaler USA Children
— · Asthma · Completed · est. 2004-09
ATAC - Quality of Life Sub-Protocol
— · Quality of Life · Completed
Study of MEDI4736 (Durvalumab) With or Without Tremelimumab Versus Standard of Care Chemotherapy in Urothelial Cancer
— · Urothelial Cancer · Active Not Recruiting · est. 2020-01-27
Study Evaluating the Clinical Benefit of SEROQUEL XR in Subjects With Schizophrenia
— · Schizophrenia · Completed · est. 2010-07
Evaluate the Safety and Efficacy of Nirsevimab in Healthy Preterm and Term Infants in China
— · Lower Respiratory Tract Infection · Completed · est. 2025-11-24
Study to Assess Effect of Next-Generation Propellant MDI on Mucociliary Clearance Vs. HFA Propellant MDI in Healthy Participants
— · Mucociliary Clearance · Completed · est. 2024-07-22
Study to Examine the Effect on Glucose Control and Safety/Tolerability of Exenatide Given Two Times a Day to Subjects With Type 2 Diabetes
— · Diabetes Mellitus, Type 2 · Completed · est. 2006-09
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
— · Chronic Rhinosinusitis With Nasal Polyps · Active Not Recruiting · est. 2027-01-13
Efficacy and Safety of Glycopyrronium/Formoterol Fumarate Fixed-dose Combination Relative to Umeclidinium/Vilanterol Fixed-dose Combination Over 24 Weeks in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
— · Chronic Obstructive Pulmonary Disease COPD · Completed · est. 2018-05-04
Crestor Versus Placebo in Subjects With Heart Failure
— · Heart Failure · Completed · est. 2007-07
18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)
— · Type 2 Diabetes · Completed · est. 2009-03
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
— · Newly Diagnosed Multiple Myeloma · Recruiting · est. 2029-01-11
AirsupraAlbuterol Sulfate
ArimidexAnastrozole
Bevespi AerosphereFormoterol Fumarate
BrilintaTicagrelor
CalquenceAcalabrutinib
CasodexBicalutamide
CrestorRosuvastatin Calcium
DalirespRoflumilast
EtcamahCamizestrant
FaslodexFulvestrant
IressaGefitinib
KoselugoSelumetinib
LokelmaSodium Zirconium Cyclosilicate
LynparzaOlaparib
NexiumEsomeprazole Magnesium
Prilosec OtcOmeprazole Magnesium
Pulmicort RespulesBudesonide
SymbicortBudesonide
Symbicort AerosphereBudesonide
TagrissoOsimertinib Mesylate
TruqapCapivasertib
Source: ClinicalTrials.gov (trials where AstraZeneca is lead sponsor; 86 active or completed) and Drugs@FDA (21 approved products). Registry data can include older or partnered programs; the company's own pipeline page is the official list.
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