Pipeline — registered trials by phase
Computerized Cognitive-Behavioral Therapy for Auditory Hallucinations
— · Schizophrenia, Schizoaffective Disorder · Completed · est. 2014-01
Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders
— · Anxiety Disorders, Depressive Disorder · Completed · est. 2023-07-01
Focused Versus Enhanced Cognitive Behavioral Therapy for Treating Women With Bulimia Nervosa
— · Eating Disorders · Completed · est. 2012-12
Alcohol and Sex Risk mHealth-Enhanced Brief Intervention for BLMSM
— · Heavy Drinking and Sexual Risk Behavior · Completed · est. 2021-09-15
Understanding How Cognitive Remediation Works
— · Schizophrenia, Schizoaffective Disorder, Chronic Mental Disorder · Completed · est. 2019-03-11
Trial of Novel, On-Demand Virtual Reality to Amplify Practice Efficacy (NO VAPE) Added to Cognitive Behavioral Therapy for Nicotine Vaping Cessation
— · NO VAPE + 12 Weeks of Standard CBT, Sham NO VAPE + 12 Weeks Standard CBT · Not Yet Recruiting · est. 2028-02
Neuromodulation for a Novel OCD Biomarker and Treatment
— · OCD · Recruiting · est. 2027-08-31
Integrated Digital Health Approach to Reduce Hazardous Alcohol Use and Chronic Pain Among Rural Populations
— · Chronic Pain, Unhealthy Alcohol Use · Not Yet Recruiting · est. 2030-11
A Novel Motivational Ecological Momentary Intervention for Anorexia Nervosa
— · Eating Disorders · Completed · est. 2015-02
Motivation and Skills Support (MASS)
— · Schizophrenia, Schizoaffective Disorder · Completed · est. 2020-05-11
Effectiveness Study of STAR (Sensory Therapies and Research) Intervention for School-Based Occupational Therapy Services for Students With Sensory Processing Challenges
— · Sensory Processing Disorder · Completed · est. 2022-02-07
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
— · Alcohol Use Disorder, Drug Use, Psychological Distress · Completed · est. 2026-03-16
Effects of Soft Robotic Exosuit on Exercise Capacity, Biomakers of Neuroplasticity, and Motor Learning After Stroke
— · Stroke · Completed · est. 2022-08-28
Self-Management Training Among Individuals With TBI
— · Traumatic Brain Injury · Not Yet Recruiting · est. 2029-03
Virtual Reality Intervention for Fear of Heights
— · Acrophobia · Completed · est. 2025-12-01
Mobile Health Technology to Promote Physical Activity in Persons With Parkinson Disease
— · Parkinson Disease · Completed · est. 2015-07
Multisite Virtual Reality Intervention for Speech Anxiety
— · Public Speaking, Speech Anxiety · Completed · est. 2025-07-23
Bridging Community Gaps Photovoice
— · Mental Illness, Social Isolation · Completed · est. 2020-09-11
Strong Families Strong Forces: Supporting Active Duty Families With Very Young Children
— · Deployment · Completed · est. 2019-03
Enhancing Cognitive and Work/School Outcomes in First Episode Psychosis Using Cognitive Self-Management Strategies
— · First Episode Psychosis (FEP) · Recruiting · est. 2029-01-31
"Recovery 4 US" - A Photovoice-based Social Media Program
— · Mental Illness, Social Isolation, Loneliness · Completed · est. 2018-07-01
Transcranial Stimulation Combined With Auditory Training
— · Difficulties Understanding Speech in Noise · Recruiting · est. 2027-03
Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder
— · Autism Spectrum Disorders · Completed · est. 2019-05-31
Asian Women's Action in Resilience and Empowerment
— · Mental Health Disorder · Completed · est. 2016-06-23
Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA?
— · Osteoarthritis of the Knee · Completed · est. 2016-01-15
Restructuring the Alpha-Gamma Code in Aging Vision
— · Aging, Visual Perception, Noninvasive Brain Stimulation · Recruiting · est. 2030-08-31
Exposure, D-Cycloserine Enhancement, and Genetic Modulators in Panic Disorder
— · Panic Disorder · Completed · est. 2014-08
D-cycloserine: A Novel Treatment for Gulf War Illness (GWDCS)
— · Gulf War Illness · Completed · est. 2019-09-15
Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
— · Social Anxiety Disorder · Completed · est. 2011-12
Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
— · Alcohol Dependence · Completed · est. 2022-01-04
No approved products listed under this sponsor in Drugs@FDA (partnered or subsidiary products may be listed elsewhere).
Source: ClinicalTrials.gov (trials where Charles River is lead sponsor; 94 active or completed) and Drugs@FDA (0 approved products). Registry data can include older or partnered programs; the company's own pipeline page is the official list.
SEC filings — insider trading forms excluded
- 8-K2026-09-24Current report (material event)
- SCHEDULE 13G/A2026-09-08SCHEDULE 13G/A
- SCHEDULE 13G2026-08-13SCHEDULE 13G
- SCHEDULE 13G/A2026-08-06SCHEDULE 13G/A
- 10-Q2026-08-05Quarterly report
- 8-K2026-08-05Current report (material event)
- 8-K2026-05-11Current report (material event)
- SD2026-05-11SD
- S-82026-05-07Employee stock plan
- 10-Q2026-05-07Quarterly report
- 8-K2026-05-07Current report (material event)
- SCHEDULE 13G/A2026-05-06SCHEDULE 13G/A
- SCHEDULE 13G2026-05-06SCHEDULE 13G
- SCHEDULE 13G2026-04-29SCHEDULE 13G
- ARS2026-03-31Annual report to holders
- DEF 14A2026-03-31Proxy statement
- SCHEDULE 13G/A2026-03-26SCHEDULE 13G/A
- 8-K2026-02-25Current report (material event)
- 8-K2026-02-18Current report (material event)
- 10-K2026-02-18Annual report
- 8-K2026-02-18Current report (material event)
- SCHEDULE 13G2026-02-12SCHEDULE 13G
- SCHEDULE 13G/A2026-02-10SCHEDULE 13G/A
- 8-K2026-01-13Current report (material event)
- 8-K2026-01-09Current report (material event)
- 8-K2025-12-03Current report (material event)
- 8-K2025-11-17Current report (material event)
- SCHEDULE 13G/A2025-11-14SCHEDULE 13G/A
- SCHEDULE 13G/A2025-11-12SCHEDULE 13G/A
- 10-Q2025-11-05Quarterly report
- 8-K2025-11-05Current report (material event)
- 8-K/A2025-09-19Current report (amended)
- 8-K2025-09-16Current report (material event)
- SCHEDULE 13G2025-08-14SCHEDULE 13G
- 10-Q2025-08-06Quarterly report
- 8-K2025-08-06Current report (material event)
- 8-K2025-05-23Current report (material event)
- SD2025-05-16SD
- SCHEDULE 13G/A2025-05-12SCHEDULE 13G/A
- 10-Q2025-05-07Quarterly report
Source: SEC EDGAR. Forms 3/4/5 and 144 (insider transactions) are intentionally left out.