Pipeline — registered trials by phase
A Norwegian Observational Trial Evaluating the Treatment of Advanced Renal Cell Cancer Patients Under Treatment of Afinitor
— · Metastatic Renal Cell Carcinoma (mRCC) · Completed · est. 2015-12
Effects of Blood Pressure Reduction on High Sensitivity C-Reactive Protein (hsCRP)
— · Hypertension · Completed · est. 2005-06
Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects
— · Atopic Dermatitis · Completed
Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures
— · Epilepsy, Partial Seizures · Completed · est. 2007-09-28
A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea
— · Non-Small-Cell Lung Carcinoma · Recruiting · est. 2026-10-31
Healthcare Resource Utilization in Adults Diagnosed With Acute Myeloid Leukemia (AML)
— · Acute Myeloid Leukemia (AML) · Completed · est. 2021-01-26
A Study of the Safety and Effectiveness of Onasemnogene Abeparvovec (Zolgensma) Intrathecal Injection in Spinal Muscular Atrophy Patients
— · Spinal Muscular Atrophy · Not Yet Recruiting · est. 2031-03-31
Follow-Up Study of Patients Previously Treated With Pimecrolimus Tablets for Atopic Dermatitis
— · Atopic Dermatitis · Completed
Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis
— · Lupus Nephritis · Completed · est. 2025-08-13
Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients
— · Chronic Renal Failure · Completed · est. 2013-06
Assessing Short-term Treatment Satisfaction and Quality of Life in Patients With Hidradenitis Suppurativa Initiated on Secukinumab.
— · Hidradenitis Suppurativa · Active Not Recruiting · est. 2026-10-10
A Study to Evaluate the Real-world Experience and Satisfaction Associated With Ofatumumab
— · Multiple Sclerosis · Completed · est. 2026-04-30
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
— · Hypertension · Completed · est. 2025-05-29
Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.
— · Heart Failure · Completed · est. 2018-10-22
Study to Evaluate the Effect of Omalizumab on Improving the Tolerability of Specific Immunotherapy in Patients With Persistent Allergic Asthma
— · Allergic Asthma · Completed · est. 2008-01
Special Drug Use Observational Study With Beovu Kit for Intravitreal Injection
— · Diabetic Macular Edema · Completed · est. 2024-06-29
Feasibility of Doctors' Rooms-based Infusion of Zoledronic Acid
— · Osteoporosis · Completed · est. 2010-07
A Study of Patient Characteristics and Treatment Patterns in Real-world Melanoma Patients Treated With Dabrafenib and Trametinib or Encorafenib and Binimetinib in Japan
— · Melanoma · Completed · est. 2022-11-20
Fabhalta Capsules Specified Drug-use Survey
— · C3 Glomerulopathy · Active Not Recruiting · est. 2028-06-30
A PMS of Jakavi® in Patients With Steroid-Refractory Graft-versus-Host Disease (SR-GvHD) in Korea
— · Graft-versus-Host Disease · Completed · est. 2026-05-08
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants
— · Hepatic Impairment · Completed · est. 2023-12-14
Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC
— · EGFR-mutant Non-small Cell Lung Cancer · Active Not Recruiting · est. 2026-10-05
Open Label Study of a Single Dose of a New Extended Long Acting Formulation of Octreotide Pamoate in Healthy Volunteers
— · Healthy Cholecystectomized · Completed · est. 2010-06
A Two-part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of KRP203 in Patients Undergoing Stem Cell Transplant for Hematological Malignancies
— · Hematological Malignancies · Completed · est. 2018-08-21
Single Dose and Multiple Dose Study to Assess Safety and Tolerability of LOU064
— · Healthy Volunteers, Atopic Diathesis and Atopic Dermatitis · Completed · est. 2020-01-27
A Study of BKM120 in Adult Japanese Patients With Advanced Solid Tumors
— · Advanced Solid Tumor · Completed · est. 2011-10
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy
— · Progressive Supranuclear Palsy (PSP) · Completed · est. 2024-10-17
Safety, Tolerability and Pharmacodynamics of QAX028 Compared to Open-label Tiotropium Bromide and Placebo in Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD) Patients.
— · COPD · Completed · est. 2008-02
Phase Ib Study of PDR001 in Combination With Regorafenib in Adult Patients With Previously Treated Metastatic Colorectal Cancer
— · Metastatic Colorectal Cancer · Completed · est. 2019-05-07
Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011
— · Normal Renal Function, Impaired Renal Function · Completed · est. 2017-09-14
First-in-human Single Ascending Dose Study of LNA043 in Patients Scheduled for Total Knee Replacement
— · Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery · Completed · est. 2018-02-07
Safety, Efficacy, Dose-finding Study of a Monoclonal Antibody in Patients With Multiple Myeloma
— · Multiple Myeloma · Completed · est. 2009-05
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
— · Pancreatic Ductal Adenocarcinoma, Non-Small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer · Recruiting · est. 2029-05-09
A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer
— · HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, HER2 + Breast Cancer, HER2 + Gastric Cancer · Completed · est. 2014-03
Pharmacokinetic Study of Alpelisib in Subjects With Hepatic Impairment.
— · Hepatic Impairment · Completed · est. 2017-10-01
Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.
— · Renal Impairment · Completed · est. 2015-03
Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney Cancer
— · Carcinoma, Adenocarcinoma, Renal Cell · Completed · est. 2011-12-31
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
— · Advanced Breast Cancer · Completed · est. 2016-03
Lapatinib in Combination With Vinorelbine
— · Cancer · Completed · est. 2012-08-21
EPO906 Therapy in Patients With Advanced Kidney Cancer
— · Kidney Neoplasms · Completed · est. 2003-08
Effects of Octreotide Acetate on Circulating Levels of Chromogranin A in Advanced Prostate Cancer Patients
— · Prostate Cancer · Completed
Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age
— · Alzheimer's Disease · Completed · est. 2016-03-11
Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD
— · Pulmonary Disease, Chronic Obstructive · Completed · est. 2022-09-15
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism
— · Priapism · Completed · est. 2023-03-28
A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP
— · Immune Thrombocytopenia (ITP) · Completed · est. 2023-09-22
A Study to Evaluate the Safety/Tolerability and Pharmacokinetics of Aliskiren in Hypertensive Pediatric and Adolescent Patients 6-17 Years of Age
— · Hypertension · Completed · est. 2010-01
Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough
— · Common Cold Associated With Cough · Completed · est. 2015-04
Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes
— · Hypereosinophilic Syndrome, Systemic Mastocytosis, Chronic Myelomonocytic Leukemia · Completed · est. 2012-01
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
— · Breast Cancer · Active Not Recruiting · est. 2027-04-14
Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
— · Breast Cancer · Completed · est. 2020-02-25
A Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation
— · Melanoma · Completed · est. 2014-12
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)
— · Amyotrophic Lateral Sclerosis (ALS) · Active Not Recruiting · est. 2026-06-23
3-arm Trial to Evaluate Pasireotide LAR/Everolimus Alone/in Combination in Patients With Lung/Thymus NET - LUNA Trial
— · Neuroendocrine Carcinoma of the Lung and Thymus · Completed · est. 2020-02-10
Study to Assess the Optimal Renoprotective Dose of Aliskiren in Hypertensive Patients With Type 2 Diabetes and Incipient or Overt Nephropathy
— · Diabetes Mellitus, Type 2 · Completed · est. 2008-04
A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection
— · Malaria · Completed · est. 2015-03
Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
— · Healthy · Completed · est. 2007-07
Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease
— · Atherosclerotic Cardiovascular Disease · Active Not Recruiting · est. 2027-05-10
Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.
— · Renal Function, Liver Transplant · Completed · est. 2016-06
A Study to Assess the Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 Diabetes
— · Diabetes Mellitus, Type 2 · Completed · est. 2006-02
8-week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension
— · Hypertension · Completed · est. 2007-08
NVA237 Versus Placebo 12-week Efficacy Study
— · Chronic Obstructive Pulmonary Disease · Completed · est. 2013-10
Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 75 Years of Age in India
— · Bacterial Meningitis · Completed · est. 2014-04
Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes
— · Diabetes Mellitus, Type 2 · Completed · est. 2008-05
Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential Hypertension
— · Hypertension · Completed · est. 2007-04
Immunogenicity, Safety and Tolerability of Two Doses of FLUAD-H5N1 Influenza Vaccine in Adult and Elderly Subjects
— · Influenza · Completed
A Randomized Phase III Study to Assess the Effect of a Longer Duration of Consolidation Treatment With Nilotinib on TFR in CP CML.
— · Philadelphia Chromosome Positive (PH+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) · Completed · est. 2020-07-08
An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood Pressure
— · Hypertension · Completed · est. 2008-04
Long Term Safety of Aliskiren Alone or With the Optional Addition of Hydrochlorothiazide in Patients With Essential Hypertension
— · Hypertension · Completed · est. 2005-10
Eltrombopag Phase III Study In Chinese Chronic ITP Patients
— · Purpura, Thrombocytopenic, Idiopathic and Hepatitis C · Completed · est. 2014-06-05
A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa
— · Parkinson's Disease · Completed · est. 2007-09
An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)
— · Prostatic Neoplasms · Active Not Recruiting · est. 2025-01-13
Study to Evaluate the Consistency of Three Consecutive Production Lots of Influenza Vaccine in Healthy Subjects 18 to 49 Years Old
— · Influenza · Completed · est. 2007-12
Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.
— · Paroxysmal Nocturnal Hemoglobinuria · Completed · est. 2024-10-17
A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril 5mg, 10mg in the Elderly
— · Hypertension · Completed · est. 2008-02
Long-term Safety and Tolerability of 0.5 mg Fingolimod in Patients With Relapsing Forms of Multiple Sclerosis
— · Relapsing Forms of Multiple Sclerosis · Completed · est. 2018-10-19
Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer
— · Non-Small Cell Lung Cancer · Active Not Recruiting · est. 2026-09-03
Safety, Tolerability and Efficacy of Everolimus With Lower Versus Higher Levels of Tacrolimus in de Novo Renal Transplant Patients
— · Renal Transplantation · Completed · est. 2005-11
Study of Efficacy and Safety LMF237 in Patients With Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Vildagliptin Monotherapy
— · Diabetes Mellitus, Type 2 · Completed · est. 2014-02
Study of Long-term Safety, Efficacy Tolerability of BYM338 in Patients With Sporadic Inclusion Body Myositis
— · Sporadic Inclusion Body Myositis (sIBM) · Completed · est. 2016-08-23
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
— · Oligometastatic Prostate Cancer (OMPC) · Recruiting · est. 2028-04-25
AfinitorEverolimus
CoartemArtemether
DiovanValsartan
ExforgeAmlodipine Besylate
Exforge HctAmlodipine Besylate
ExjadeDeferasirox
FabhaltaIptacopan Hydrochloride
GleevecImatinib Mesylate
KisqaliRibociclib Succinate
Kisqali Femara Co-Pack (Copackaged)Letrozole
LocametzGallium Ga-68 Gozetotide
MayzentSiponimod
MekinistTrametinib
MyforticMycophenolate Sodium
NeoralCyclosporine
NetspotGallium Dotatate Ga-68
PiqrayAlpelisib
PluvictoLutetium Lu-177 Vipivotide Tetraxetan
PromactaEltrombopag Olamine
Promacta KitEltrombopag Olamine
RhapsidoRemibrutinib
SandostatinOctreotide Acetate
ScemblixAsciminib Hydrochloride
SimulectBasiliximab
TafinlarDabrafenib Mesylate
TegretolCarbamazepine
TrileptalOxcarbazepine
VanrafiaAtrasentan Hydrochloride
VijoiceAlpelisib
ZortressEverolimus
ZykadiaCeritinib
Source: ClinicalTrials.gov (trials where Novartis is lead sponsor; 80 active or completed) and Drugs@FDA (31 approved products). Registry data can include older or partnered programs; the company's own pipeline page is the official list.
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